Colgate Total<sup>®</sup> Toothpaste

Colgate Total® Toothpaste

One of the most extensively tested and researched toothpastes in the world

Ingredients

Active ingredients

Sodium Fluoride 0.24% (0.15% w/v fluoride ion) - Anticavity, Triclosan 0.30% Antigingivitis

Inactive ingredients

Aqua, Hydrated Silica, Glycerin, Sorbitol, PVM/MA Copolymer, Sodium Lauryl Sulphate, Aroma, CI 77891, Cellulose Gum, Sodium Hydroxide, Carrageenan, Sodium Saccharin, Limonene.

Mode of Action

Unlike ordinary toothpastes* Colgate Total® adheres to hard and soft tissue for whole mouth protection. Ordinary anticavity toothpastes only protect the hard tissue, which is 20% of the mouth1. 80% of the mouth is soft tissue.1 Bacteria develop on soft tissue surfaces, and can act as a reservoir to start recolonizing teeth and gums right after toothbrushing.

* Defined as non-antibacterial fluoride toothpaste.
Defined as fluoride for cavity protection, plus 12-hour antibacterial protection against gingivitis.
1. Amornchat C, Kraivaphan P, Triratana T. Mahidol Dent J. 2004:24:103-111.

Proof of Efficacy

Whole mouth antimicrobial effects after oral hygiene: comparison of three dentifrice formulations.

Fine DH, Sreenivasan PK, McKiernan M, Tischio-Bereski D, Furgang D.

RESULTS:
For all 4 oral sites and 6 organisms evaluated in each site, the TCN/C demonstrated significant reductions (49%-83%) as compared with the other treatments (p < 0.01). The SnF (2)/SHMP group showed significant reductions of 14%-43% for 14 of 24 outcomes as compared with the NaF group (p < 0.01), with no differences in 10 outcomes.

CONCLUSIONS: The TCN/C dentifrice formulation consistently demonstrated significant reductions for a range of microorganisms in diverse oral sites in comparison with the NaF, or the SnF(2)/SHMP dentifrice formulations as seen 12 h after brushing.

Drug Facts

Active Ingredients: Sodium Fluoride (0.24%) (0.15% w/v Fluoride Ion), Triclosan (0.3%).

Purpose: Anticavity, Antigingivitis.

Use: Aids in the prevention of: cavities; plaque; gingivitis.

Warnings: Keep out of the reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away. Ask a dentist before use if you have bleeding or redness lasting more than 2 weeks; pain, swelling, pus, loose teeth, or more spacing between teeth. These may be signs of periodontitis, a serious form of gum disease.

Directions: Supervise children as necessary until capable of using without supervision. Antiplaque and antigingivitis use not proven in children. Adults and Children 6 Years of Age and Older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or a physician. Children Under 12 Years: Instruct in good brushing and rinsing habits (to minimize swallowing). Children Under 6 Years: Do not use unless directed by a dentist or a physician.

Inactive Ingredients: Water, Hydrated Silica, Glycerin, Sorbitol, PVM/MA Copolymer, Sodium Lauryl Sulfate, Flavor, Cellulose Gum, Sodium Hydroxide, Propylene Glycol, Carrageenan, Sodium Saccharin, Titanium Dioxide.

Questions? 1-800-468-6502